MadeMed vs. Hims: A Peptide Addition vs. Stacked PDE5 Inhibitors
Both compounded combinations, targeting genuinely different mechanisms.
Reviewed by the EdClinic Editorial Team · our research standards · not a substitute for professional medical adviceMadeMed's peptide-inclusive troche against Hims' stacked-PDE5 chewable — both compounded combinations, targeting different mechanisms.
MadeMed's approach
Tadalafil combined with PT-141 and oxytocin — one PDE5 inhibitor plus a peptide acting on the arousal pathway directly.
MadeMed
Compounded tadalafil through a licensed pharmacy network, positioned as a lower-cost alternative to brand-name treatment for people who qualify after evaluation.
Compounded medication notice: compounded formulations are not FDA-approved. Compounding pharmacies prepare medications under a licensed clinician’s prescription; effectiveness and safety have not been independently evaluated by the FDA.
View Offer Paid LinkHims' approach
Sildenafil, tadalafil, and vardenafil combined in personalized doses — multiple PDE5 inhibitors stacked together, no peptide component.
The actual comparison
Hims doubles and triples down on blood flow specifically. MadeMed adds a genuinely separate mechanism through PT-141. If blood flow alone hasn't been the issue, MadeMed's peptide inclusion targets something Hims' formula doesn't touch.